Thank you for the DNS article. You gave a lot of great information and it is explained well though I wonder what a corrupt DNS looks like? I picture the hosts file in windows and it seems pretty basic. I am sure there is more to it than corrupting a simple text (version) of a DNS list on a computer, router, etc.
We have had issues with a software upgrade where one resolution is to run (IIS reset) and ipconfig /flushdns. I think that flushing the DNS isn’t likely to help as a repeated ‘temp’ fix because I can’t believe it can get corrupted that fast, especially since the software is used internally about 75% of the time and 25% accessed through the internet by our techs.
The software requires we use DotNet4 and we are running it on a hefty new server in a vmware configuration on W2k8r2 64bit which is more than the required system for this software. Even before the upgrade while on a different server, the software was having issues. The client side of the software ends up running slower and slower. I may not understand the process entirely but I think it may be due to memory usage or leaks from the software causing the software cache or pool to become full.
These are unwanted effects that you consider are linked to taking a medicine. Side effects also include any effects from: misuse, abuse, an error in the way the medicine has been given or overdose (taking too much medicine). Reports can be made for any medicine (including specials and unlicensed products), any vaccine, herbal product, and complimentary remedies such as homeopathic remedies, blood factors (. factors I to XIII) and immunuloglobulins (. anti-D (RHO) immunoglobulin). You can even report suspected side effects from a drug you think might be happening as a result of interactions with food and drink.
Severe deficiency of niacin in the diet causes the disease pellagra , which is characterized by diarrhea, dermatitis, and dementia, as well as Casal's necklace lesions on the lower neck, hyperpigmentation, thickening of the skin, inflammation of the mouth and tongue, digestive disturbances, amnesia, delirium, and eventually death, if left untreated.  Common psychiatric symptoms of niacin deficiency include irritability, poor concentration, anxiety, fatigue, restlessness, apathy, and depression.  Studies have indicated that, in patients with alcoholic pellagra, niacin deficiency may be an important factor influencing both the onset and severity of this condition. Patients with alcoholism typically experience increased intestinal permeability , leading to negative health outcomes.