Oxymetholone synthesis

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There is limited information available on the pharmacokinetics of oxymetholone. [4] It appears to be well-absorbed with oral administration . [4] Oxymetholone has very low affinity for human serum sex hormone-binding globulin (SHBG), less than 5% of that of testosterone and less than 1% of that of DHT. [1] The drug is metabolized in the liver by oxidation at the C2 position, reduction at the C3 position, hydroxylation at the C17 position, and conjugation . [4] [2] The C2 hydroxymethylene group of oxymetholone can be cleaved to form mestanolone (17α-methyl-DHT), which may contribute to the effects of oxymetholone. [3] The elimination half-life of oxymetholone is unknown. [2] Oxymetholone and its metabolites are eliminated in the urine . [1] [2]

Oxymetholone synthesis

oxymetholone synthesis

There is limited information available on the pharmacokinetics of oxymetholone. [4] It appears to be well-absorbed with oral administration . [4] Oxymetholone has very low affinity for human serum sex hormone-binding globulin (SHBG), less than 5% of that of testosterone and less than 1% of that of DHT. [1] The drug is metabolized in the liver by oxidation at the C2 position, reduction at the C3 position, hydroxylation at the C17 position, and conjugation . [4] [2] The C2 hydroxymethylene group of oxymetholone can be cleaved to form mestanolone (17α-methyl-DHT), which may contribute to the effects of oxymetholone. [3] The elimination half-life of oxymetholone is unknown. [2] Oxymetholone and its metabolites are eliminated in the urine . [1] [2]

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