Oral exemestane 25 mg/day for 2–3 years of adjuvant therapy was generally more effective than 5 years of continuous adjuvant tamoxifen in the treatment of postmenopausal women with early-stage estrogen receptor-positive/unknown receptor status breast in a large well-designed [ citation needed ] trial. Preliminary data from the open-label TEAM trial comparing exemestane with tamoxifen indicated in 2009 that exemestane 25 mg/day is also effective in the primary adjuvant treatment of early-stage breast cancer in postmenopausal women. 
For many endurance athletes, the toughest part of a cycle with Winstrol tabs involves finding the dose that works best for their unique needs. Bodybuilders who want to harden or even grow their muscles may use anywhere from 50mg to 100mg per day, and those interested in cutting fat while retaining hard-earned gains generally take 50mg per day during a six-to eight-week cutting cycle. According to a variety of experienced users who want to boost their strength and improve their recovery without gaining (or losing) muscle mass, the best dose is anywhere from 20mg to 50mg per day. Starting with the 20mg and working your way up to a maximum of 50mg over the course of two weeks is a great way to determine which dose will work best for your needs.